motivated by curiosity.

Encoding of rules by neurons in the human dorsolateral prefrontal cortex

11.21.12 Posted in Human Neurophysiology Studies by

We use rules to extend learned behavior beyond specific instances to general scenarios. The prefrontal cortex (PFC) is thought to play an important role in representing rules, as evidenced by subjects who have difficulty in following rules after PFC damage and by animal studies demonstrating rule sensitivity of individual PFC neurons. How rules are instantiated […]


Lesion procedures in psychiatric neurosurgery

11.16.12 Posted in Reviews by

Lesion procedures for psychiatric indications have a history that spans more than a century. In this review, we provide a brief history of psychiatric surgery and address the most recent literature on lesion surgery for the treatment of anxiety and mood disorders.